Publications

Intervacc´s collaborators have published and participated in a number of doctoral thesis works and peer reviewed scientific journals with good ranking. Here is a list of relevant publications:

Referee- reviewed articles in international papers

CategoryPublicationYear
Strangvac clinical trialsIntramuscular vaccination with Strangvac is safe and induces protection against equine strangles caused by Streptococcus equi, Vaccine 38, 4861-4868 , Carl Robinson, Andrew S. Waller, Lars Frykberg, Margareta Flock, Olof Zachrisson, Bengt Guss and Jan-Ingmar Flock.2020
Strangvac early trialsGetting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. PLoS Pathogen. Published 18 sep 2009, doi: 10.1371/journal.ppat.1000584, Bengt Guss, Margareta Flock, Lars Frykberg, Andrew S. Waller, Carl Robinson, Ken C. Smith, and Jan-Ingmar Flock. 2009
Strangvac early trialsStrangvac: A recombinant fusion protein vaccine that protects against strangles, caused by Streptococcus equi Vaccine, 2018 Mar 7;36(11):1484-1490, Robinson, C., Frykberg, L., Flock, M., Guss, B., Waller, A., Flock, J-I 2017
Strangvac early trialsProtective effect of vaccination with recombinant proteins from Streptococcus equi subspecies equi in a strangles model in the mouse. Vaccine 24:4144-4151. Flock, M., Karlström, Å., Lannergård, J., Guss, B. and Flock, J.-I. 2006
Strangvac early trialsVaccination of horses against strangles using recombinant antigens from Streptococcus equi. Vaccine 25:3629-3635. Waller, A., Flock, M., Smith, K., Robinson, C., Mitchell, Z., Karlström, A., Lannergård, J., Bergman, R., Guss, B. and Flock JI2007
Strangvac early trialsRecombinant Streptococcus equi proteins protect mice in challenge experiments and induce immune response in horses. Infect Immun. 72:3228-3236. Flock, M., Jacobsson, K., Hirst, T., R., Franklin, A., Guss, B., and Flock, J.-I. 2004
Strangvac targetsThe streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen. J Biol Chem 285: 35803-35813. van Wieringen T, Kalamajski S, Lidén A, Bihan D, Guss B, Heinegård D, Farndale RW and Rubin K.2010
Strangvac targetsIdentification of a novel collagen-like protein, SclC, in Streptococcus equi using signal phage display.Vet Microbiol 104:179-188. Karlström, Å., Jacobsson, K., Flock, M., Flock,J.-I., and Guss B.2004
Strangvac targetsSclC is a member of a novel family of collagen-like proteins in Streptococcus equi subspecies equi that are recognized by antibodies against SclC. Vet Microbiol 114:72-8. Karlström, Å., Jacobsson, K. and Guss, B. 2006
Strangvac targetsIdeE, an IgG-endopeptidase of Streptococcus equi ssp equi. FEMS Microbiology Letters 262:230-235. Lannergård, J. and Guss, B. 2006
Strangvac targets CNE, a collagen-binding protein of Streptococcus equi. FEMS Microbiol. Lett. 222:69-74. Lannergård, J., Frykberg, L. and Guss, B.2003
Strangvac targetsShot-gun phage display mapping of two streptococcal cell-surface proteins. Microbiol Res.152:1-8. Jacobsson, K., Jonsson, H., Lindmark, H., Guss, B., Lindberg, M. and Frykberg. L. 1997
Strangvac targetsA protein G related cell surface protein in Streptococcus zooepidemicus. Infect Immun 63:2968-2975. Jonsson, H., Lindmark, H. and Guss. B. 1995
Research StranglesNovel seM-types of Streptococcus equi subsp. equi identified in isolates circulating in Argentina Equine Vet J. Carla P Bustos, Alejandra J Muñoz, Nora Guida, Andrew Waller, María Mesplet.2022
Research StranglesSurveillance of strangles in UK horses between 2015 and 2019 based on laboratory detection of Streptococcus equi. Vet Rec Dec;189(12):e948, DOI: 10.1002/vetr.948. Abigail McGlennon, Andrew Waller, Kristien Verheyen, Josh Slater, John Grewar, David Aanensen, Richard Newton.2021
Research StranglesStreptococcus equi infections: current best practice in the diagnosis and management of ‘strangles’. UK-Vet EquineVol. 5, No. Sup2 David Rendle, Nic de Brauwere, Gayle Hallowell, Philip Ivens, Abigail McGlennon, Richard Newton, Jo White, Andrew Waller.2021
Research StranglesGlobetrotting strangles: the unbridled national and international transmission of Streptococcus equi between horses Microb Genom. Catriona Mitchell, Karen F Steward, Amelia R L Charbonneau, Saoirse Walsh, Hayley Wilson, John F Timoney, Ulli Wernery, Marina Joseph, David Craig, Kees van Maanen, Annelies Hoogkamer-van Gennep, Albertine Leon, Lucjan Witkowski, Magdalena Rzewuska, Ilona Stefańska, Monika Żychska, Gunther van Loon, Ray Cursons, Olivia Patty, Els Acke, James R Gilkerson, Charles El-Hage, Joanne Allen, Hiroshi Bannai, Yuta Kinoshita, Hidekazu Niwa, Teótimo Becú, John Pringle, Bengt Guss, Reinhard Böse, Yvonne Abbott, Lisa Katz, Bernadette Leggett, Tom C Buckley, Shlomo E Blum, Fátima Cruz López, Ana Fernández Ros, Maria Cristina Marotti Campi, Silvia Preziuso, Carl Robinson, J Richard Newton, Ellen Schofield, Ben Brooke, Mike Boursnell, Nicolas de Brauwere, Roxane Kirton, Charlotte K Barton, Khalil Abudahab, Ben Taylor, Corin A Yeats, Richard Goater, David M Aanensen, Simon R Harris, Julian Parkhill, Matthew T G Holden, Andrew Waller.2021
Research StranglesHorses vaccinated with live attenuated intranasal strangles vaccine seroconvert to SEQ2190 and SeM Equine Vet J, Ashley G Boyle, Catriona Mitchell, Darko Stefanovski, Andrew S Waller. 2021
Research StranglesSeroprevalence of Streptococcus equi subspecies equi in Croatia - Short communication Acta Vet Hung, Zrinka Štritof, Catriona Mitchell, Nenad Turk, Josipa Habuš, Suzana Hađina, Matko Perharić, Andrew S Waller.2021
Research StranglesInfection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response. Infect Immun. 78:854-864. Rönnberg E, Guss B and Pejler G. 2010
Research StranglesA secreted collagen- and fibronectin-binding streptococcal protein modulates cell-mediated collagen gel contraction and interstitial fluid pressure. J Biol Chem 283:1234-1242. Lidén., A., van Wieringen, T., Lannergård, J., Kassner, A., Heinegård, D., Reed, R.K., Guss, B. and Rubin, K. 2008
Research StranglesA fibronectin-binding protein from Streptococcus equi binds collagen and modulates cell-mediated collagen gel contraction. Biochem Biophys Res Com 340:604-610. Lidén, Å., Karlström, Å., Lannergård, J., Kalamajski, S., Guss, B., Rubin, K. and Rydén, C. 2006
Research StranglesStudies of fibronectin-binding proteins in Streptococcus equi. Infect Immun 73:7243-7251. Lannergård, J., Flock, M., Johansson, S., Flock, J.-I., and Guss, B. 2005
Research StranglesFNE belongs to a novel family of fibronectin-binding and collagen-binding proteins of Streptococcus equi subspecies equi (manuscript in Jonas Lannergårds doctoral thesis, SLU ISBN 91-576-7129-X). Lannergård, J. and Guss, B 2006
Research StranglesComparison of the fibronectin-binding protein FNE from Streptococcus equi subspecies equi with FNZ from S. equi subspecies zooepidemicus reveals a major and conserved difference. Infect Immun. 69: 3159-3163. Lindmark, H., Nilsson, M. and Guss, B. 2001
Research StranglesSFS, a novel fibronectin-binding protein from Streptococcus equi, inhibits the binding between fibronectin and collagen. Infect. Immun. 67: 2383-2388. Lindmark, H. and Guss, B. 1999
Research StranglesPulsed-field gel electrophoresis and distribution of the genes zag and fnz in isolates of Streptococcus equi. Res Vet Sci. 66:93-99. Lindmark, H., Jonsson, P., Olsson-Engvall, E. and Guss, B. 1999
Research StranglesFibronectin-binding protein of Streptococcus equi subspecies zooepidemicus. Infect Immun 64: 3993-3999. Lindmark, H., Jacobsson, K., Frykberg, L. and Guss, B. 1996
Research streptococcalFunctional Insights into the High-Molecular-Mass Penicillin-Binding Proteins of Streptococcus agalactiae Revealed by Gene Deletion and Transposon Mutagenesis Analysis. J Bacteriol, Luchang Zhu, Prasanti Yerramilli, Layne Pruitt, Abhishek Mishra, Randall Olsen, Stephen B Beres, Andrew Waller, James Musser. 2021

Avhandlingar

1”Characterization of adhesive extracellular proteins from Streptococcus equi”. Doctoral thesis, Swedish University of Agricultural Sciences. Hans Lindmark (1999) ISSN 1401-6249
ISBN 91-576-5488-3
2“Development of a vaccine against strangles”. Karolinska Institutet, Margareta Flock (2005) ISBN 91-7140-500-3
3“Collage-like proteins in horse pathogenic Stretococcus equi”. Doctoral thesis, Swedish University of Agricultural Sciences, Åsa Karlström (2005)ISSN 1652-6880
ISBN 91-576-6998-8
4“Potentially virulence-related extracellular proteins of Streptococcus equi”. Doctoral thesis, Swedish University of Agricultural Sciences, Jonas Lannergård (2006) ISSN 1652-6880
ISBN 91-576-7129-X